Top Python Jobs in London

Partner with startup founders and engineering teams to architect, evaluate, deploy, and scale LLM applications on the Claude Developer Platform. Serve as a technical advisor throughout adoption, lead technical evaluations, develop AI performance frameworks, communicate customer insights to Product and Engineering, and represent Anthropic at customer sites and industry events.

Create high-quality keyframe animation for primary and secondary characters and elements in story-driven visual effects and immersive projects. Collaborate with Animation Leads, Supervisors, Production, and team members; complete assigned shots on schedule; submit work for review; incorporate feedback; and adapt to changing creative and technical requirements.

Serves as the dedicated technical partner for customers using Era4’s AI and HPC infrastructure. Responsibilities include onboarding, workload and capacity planning, cluster and network readiness, technical documentation, SLA and KPI reporting, incident escalation, root cause analysis, governance, and roadmap input. The role requires customer-facing technical experience, Linux troubleshooting, GPU infrastructure knowledge, data-centre networking, and familiarity with ITIL-aligned service processes.

Build and operate backend services, internal developer platforms, CI/CD systems, testing capabilities, and developer tooling using Python. Improve developer productivity and experience through scalable paved paths, cloud-native systems, distributed architectures, and AI-native development workflows. Partner with engineering teams to identify friction, measure platform effectiveness, and enable autonomous software delivery.

Build and operate cloud and on-premises platforms supporting infrastructure provisioning and application deployment. Develop CI/CD capabilities, improve developer experience, automate workflows with scripting and IaC, and enforce security and governance practices. Collaborate on cloud architecture, support platform users, participate in on-call and maintenance activities, and promote DevOps practices while mentoring junior engineers.

Productionize and operate reliable machine learning systems across training, evaluation, deployment, monitoring, and LLM feature delivery. Build scalable batch and streaming data pipelines, containerized training environments, cloud infrastructure, feature transformations, and observability systems. Develop internal Python tooling, manage compute resources, ensure reproducibility and testing, and collaborate with ML scientists, backend engineers, and data engineers. Mentor peers and support secure, modular ML services throughout the model lifecycle.

Lead technical pre-sales engagements for Twilio communications products across new business and strategic accounts. Partner with Account Executives on qualification, demonstrations, proofs of concept, RFPs, technical presentations, and solution design. Discover customer needs, recommend architectures, demonstrate APIs, build trusted-advisor relationships, resolve technical concerns, create reusable enablement materials, contribute to the presales community, and mentor junior engineers.

Lead the design, deployment, and operation of scalable data pipelines and cloud infrastructure for Kpler’s marine insurance initiative. Build containerized AWS services using Python, Docker, Kubernetes, Airflow, and Terraform; manage PostgreSQL and Kafka/Flink streaming systems; establish observability standards; provide technical direction; collaborate cross-functionally; and mentor engineers.

Lead and own major components of DuckDuckGo's privacy technology using Go, Node.js, Python, and Perl. Design and implement privacy features, improve search and AI features without compromising privacy, build tracker-detection features, participate in privacy reviews and audits, and mentor engineers over time.

Lead data-driven digital transformation solutions for large capital construction projects. Responsibilities include understanding client problems, advising on best practices, directing technical teams, mentoring junior staff, developing Azure, Fabric, Power BI, and Python solutions, productizing client solutions, and improving internal data processes. The role requires strong communication, analytical thinking, construction or engineering experience, and the ability to translate complex concepts for varied audiences.

Staff Full Stack Engineer responsible for architecting and building integration-heavy, event-driven systems for renewable energy products. The role focuses on backend development with Python and AWS serverless technologies, while contributing to React and TypeScript frontend work. Responsibilities include integrating pricing, tendering, data, billing, and risk systems; automating commercial workflows; delivering new product categories; solving ambiguous technical problems; and maintaining high standards for testing, documentation, and code quality.

Own product metrics definitions and trees, investigate anomalies and conversion bottlenecks, validate hypotheses, conduct data mining, and prioritize growth opportunities. Design, monitor, and analyze A/B tests, including sample sizing, randomization, guardrail metrics, data tracking, quality checks, and actionable recommendations. Collaborate with Product and functional leads in a fully remote environment.

Lead and grow the EMEA Forward Deployed Engineering team to design, deliver, and deploy applied AI/ML solutions. Hire and mentor engineers, drive 0-to-1 product development, ensure production-grade architectures, monitor models in production, manage AI risk and GDPR compliance, and align technical work with business outcomes while communicating with stakeholders.

Entry-level audit technology graduate role in BDO’s London Technology Risk Assurance team. The role offers Data Analytics or IT Controls work, including financial application controls testing, cybersecurity risk assessments, data analysis, financial information validation, and audit dashboards. Graduates work toward CFAB, ICAEW Power BI, CISA, and other qualifications over three years, with client exposure and support from experienced colleagues. Successful completion leads to accountant qualification and a permanent role.

Four-year school leaver apprenticeship in audit technology, supporting Technology Risk Assurance through IT controls testing, cyber risk assessments, data analysis, financial information validation, and audit dashboards. Apprentices work with audit teams and clients while balancing professional responsibilities with study. Roles are available in Controls or Data across Birmingham, London, Reading, and Manchester, with office attendance and client collaboration required.

Designs, builds, and operates reliable cloud infrastructure across AWS and Azure. Responsibilities include developing Terraform infrastructure as code, managing EKS and AKS Kubernetes clusters, maintaining CI/CD pipelines, improving security and cost efficiency, troubleshooting distributed infrastructure issues, implementing monitoring and alerting, and collaborating with engineering and architecture teams on platform standards and documentation.

Analyze methanol and derivative chemical markets through supply-demand balances, trade flows, operating schedules, price forecasts, and market models. Conduct primary and secondary research, identify data sources, transform and analyze data, and author Chemical Economics Handbook reports. Provide client insights, presentations, and responses to data requests while collaborating with subject-matter experts and global teams to deliver accurate, timely market intelligence.

Leads statistical programming for pharmaceutical clinical development studies. Develops and validates SAS and R programs, SDTM and ADaM datasets, specifications, tables, listings, figures, and regulatory submission deliverables. Oversees CRO programming activities, supports clinical reports and FDA submissions, maintains programming standards, contributes to CRF and validation planning, and collaborates with clinical, regulatory, vendor, and development teams.

Build and deploy scalable AI applications, intelligent agents, and AI-powered features in production. Collaborate with research, data science, and product teams; evaluate emerging AI technologies; and promote responsible AI through bias detection, explainability, and safety alignment. The role requires production machine learning experience, strong Python and AI framework skills, cloud and MLOps experience, and expertise in deep learning, NLP, and large language models.

Partner with enterprise customers to identify AI use cases, validate feasibility, and deliver tailored applications, templates, and integrations using WRITER’s platform, APIs, Knowledge Graph, and LLMs. Translate complex AI concepts into actionable recommendations, collaborate with Product and Engineering, improve technical integration processes, and drive customer adoption, value, and expansion.

Lead a CloudOps/SRE team supporting mission-critical AWS services for a UK public-sector client. Responsibilities include cloud architecture, Infrastructure-as-Code with Terraform and Ansible, CI/CD automation, monitoring, incident resolution, application support, disaster recovery, security compliance, cost optimization, and team management. The role requires strong leadership, hands-on cloud operations expertise, and eligibility for DBS and UK security clearance.

Develop and scale Python-based APIs, web services, mobile and voice-assistant integrations, and internal editorial systems supporting high-traffic digital products. The role involves writing clean, tested code; collaborating through reviews and paired programming; working with databases and ORM frameworks; applying RESTful and software engineering principles; and contributing to continuous integration. Experience with modern Python frameworks, GraphQL, asyncio, Docker, AWS, Kubernetes, and search platforms is advantageous.

Build and scale AI agent systems that autonomously execute workflows and integrate with enterprise data, services, vector databases, search systems, and external APIs. Develop backend infrastructure, high-throughput APIs, orchestration, memory, security, and asynchronous workflows. Ensure reliability through monitoring, observability, testing, CI/CD, and fault tolerance. Collaborate with product, research, data, and UX teams, contribute to architecture and code reviews, and develop frontend tooling for agent management.

Build and lead application security for WRITER’s enterprise AI platform. Responsibilities include threat modeling, secure architecture reviews, SAST/DAST and CI/CD security automation, code reviews, secure coding standards, penetration testing, vulnerability remediation, and protection of AI agents, data pipelines, and model training environments. The role also researches emerging LLM security threats and partners with engineering teams to embed scalable security controls.

Build secure, scalable generative AI services, applications, APIs, microservices, and agentic workflows for enterprise customers. Own system architecture from proposal through deployment, develop React and TypeScript interfaces, and partner with DevOps on continuous deployment, monitoring, logging, performance, and security. Collaborate with product, data science, and engineering teams while mentoring peers and delivering resilient production software.