Isomorphic Labs Logo

Isomorphic Labs

Principal Software Engineer (ML Infrastructure), London

Posted An Hour Ago
Be an Early Applicant
In-Office
London, Greater London, England, GBR
Expert/Leader
In-Office
London, Greater London, England, GBR
Expert/Leader
Build and evolve large-scale machine learning infrastructure for distributed training and inference workloads. The role involves improving platform reliability, deploying research-supporting agents, enabling scalable ML development, and partnering with engineering, research, and product teams. Strong Python and large-scale infrastructure experience are essential; Kubernetes, GCP, internal platform development, and multi-cloud experience are advantageous. The position follows a hybrid model requiring three office days per week in London.
The summary above was generated by AI

Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.

The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery. 

Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.

The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you. 


About Iso

Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.

Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.

We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.

Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.


Your impact 

This is an exciting opportunity for a small number of innovative and versatile software engineers to work in a fast-paced and research-centric environment. 

You will collaborate extensively with internal engineering and research teams to evolve the foundational infrastructure that makes it easy to train and deploy novel machine learning models over vast (and growing) pools of compute and data.

For this role we are looking for individuals with experience of designing and evolving complex systems at significant scale. Domain knowledge of ML inference, training or research infrastructure will be a strong advantage, though we encourage applications from candidates with a record of exceptional impact in any field.

What you will do 
  • Evolve the ML infrastructure platform to accelerate both human and agent-driven research at scale
  • Explore options to deploy agents to increase the robustness and reliability of the platform
  • Develop the platform to enable the next generation of distributed, performance-critical training and inference workloads 
  • Partner closely with engineering, research and product teams to identify and deliver impact
Skills and qualifications Essential:
  • Demonstrated ability to independently identify opportunities, deliver solutions and work effectively in cross-functional teams
  • Experience building and evolving infrastructure or platforms at significant scale
  • Strong Python programming (though familiarity with any particular library is not required)
Nice to have:
  • Domain knowledge of ML inference, training or research infrastructure
  • Strong hands-on experience building for Kubernetes
  • Experience providing platforms to internal customers
  • Experience with Google Cloud Platform (GCP)
  • Experience with multi-cloud environments

Culture and values

We are guided by our shared values. It's not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it. 

Thoughtful
Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.

Brave
Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.

Determined
Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.

Together
Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.


Creating an extraordinary company

We believe that to be successful we need a team with a range of skills and talents. We're building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.

We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.


Hybrid working

It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and would require you to be able to come into the office 3 days a week (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.

Please note that when you submit an application, your data will be processed in line with our privacy policy.

>> Click to view other open roles at Isomorphic Labs

HQ

Isomorphic Labs London, England Office

London, United Kingdom

Similar Jobs

44 Minutes Ago
Easy Apply
Hybrid
London, Greater London, England, GBR
Easy Apply
Expert/Leader
Expert/Leader
Big Data • Cloud • Software • Database
Leads MongoDB’s EMEA marketing strategy and regional execution, driving pipeline, revenue, customer acquisition, and expansion. Partners with Sales and global marketing leaders to align investments, account engagement, demand generation, developer programs, partner initiatives, and events. Transforms regional operations through AI, automation, shared capabilities, and scalable workflows. Builds high-performing teams, provides market insight, manages cross-functional alignment, and improves marketing measurement and business impact across enterprise technology markets.
Top Skills: Account-Based Marketing (Abm)AIAWSGCPMarketing AutomationAzureMongoDB
45 Minutes Ago
Easy Apply
Hybrid
London, Greater London, England, GBR
Easy Apply
Senior level
Senior level
Big Data • Cloud • Software • Database
Own strategic customer relationships and portfolios for MongoDB’s largest customers. Advise on MongoDB best practices, deployment health, technical strategy, consumption, and growth. Lead account planning, executive business reviews, risk mitigation, escalations, renewals, and churn forecasting while coordinating Sales, Professional Services, Engineering, and Product teams. Document customer activity, provide product feedback, build Customer Success processes, and mentor or onboard team members.
Top Skills: AWSCloud InfrastructureDatabase TechnologyGainsightGCPAzureMongoDBMongodb AtlasSalesforce
59 Minutes Ago
In-Office
London, Greater London, England, GBR
Entry level
Entry level
Information Technology • Software • Financial Services • Big Data Analytics
Design, develop, test, deploy, and maintain scalable Java applications, services, and platforms supporting investment and business workflows. Build distributed systems, APIs, data platforms, and event-driven architectures; modernize existing technology; improve performance, reliability, and scalability; and contribute to architecture and technical strategy. Partner with users and engineering teams throughout the software development lifecycle to deliver production-quality solutions.
Top Skills: APIsBuild SystemsCi/CdCloud InfrastructureContainerized EnvironmentsDistributed DatabasesJavaMessaging TechnologiesRelational DatabasesSource ControlSQL

What you need to know about the London Tech Scene

London isn't just a hub for established businesses; it's also a nursery for innovation. Boasting one of the most recognized fintech ecosystems in Europe, attracting billions in investments each year, London's success has made it a go-to destination for startups looking to make their mark. Top U.K. companies like Hoptin, Moneybox and Marshmallow have already made the city their base — yet fintech is just the beginning. From healthtech to renewable energy to cybersecurity and beyond, the city's startups are breaking new ground across a range of industries.

Sign up now Access later

Create Free Account

Please log in or sign up to report this job.

Create Free Account