Senior Manager, Data Sciences

At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it.

Are you a hands-on data scientist with a passion for turning complex, multi-modal data into actionable insights that shape clinical decisions? Bristol Myers Squibb is seeking a Senior Manager, Data Science to join our Drug Development Data Science & Advanced Analytics (DSAA) team.

This is a new role for a state-of-the-art individual contributor who thrives at the interface of computational science, statistical rigour, and drug development. You will execute and drive exploratory and confirmatory analyses across a rich variety of data types — from clinical trial data to genomics, proteomics, imaging, and beyond — contributing directly to decisions that advance our global development pipeline.

Data Science & Analytics

• Develop and apply novel computational methods for patient segmentation, biomarker discovery, and hypothesis generation from multimodal clinical and omics datasets, in partnership with Translational, Clinical, and Statistical Scientists
• Execute data science analyses on datasets from BMS clinical trials and real-world data cohorts, spanning genomics, proteomics, imaging, flow cytometry, and other high-dimensional biomarker data types
• Develop innovative approaches to integrating, mining, and visualising diverse, high-dimensional, and disparate datasets generated across early-to-late phase drug development
• Formulate, implement, test, and validate predictive models and build efficient, automated processes for delivering modelling results at scale
• Apply modern machine learning capabilities — including AI/ML, deep learning, NLP, causal ML, and explainable AI — across multiple data modalities and clinical development contexts
• Apply statistically rigorous approaches to clinical trial data, including survival analysis, longitudinal/mixed-effects modelling, and appropriate handling of missing data and censoring
• Contribute to the scientific and statistical strategy of drug development programs, including the development of predictive biomarkers, novel trial designs, and precision medicine approaches

Data Engineering & Reproducibility

• Build and maintain well-structured, reproducible, version-controlled analytical pipelines and codebases using Python, R, SQL, and cloud platforms
• Develop and apply data quality frameworks to assess and ensure fitness-for-purpose of diverse data sources for specific analytical questions
• Implement strong model evaluation practices including cross-validation strategies, calibration assessment, and transparent reporting of model performance and limitations
• Build scalable, automated processes for delivering analytical results across multiple programs and data types

Collaboration & Technical Contribution

• Partner with lead and protocol statisticians in contributing to statistical analysis plans (SAPs) for exploratory data science analyses supporting drug development programs
• Collaborate with cross-functional teams including clinicians, translational medicine scientists, biostatisticians, data engineers, and IT/engineering professionals
• Contribute to team excellence through code reviews, technical mentorship, and raising the overall engineering and methodological standards of the team
• Communicate analytical strategies and results clearly and effectively to both technical and non-technical stakeholders, with strong data presentation and visualisation skills
• Manage and coordinate deliverables across concurrent, fast-paced projects within tight timelines

Required Qualifications:

• PhD in a relevant quantitative field (e.g., Computational Biology, Biostatistics, Statistics, Biomedical Engineering, or Computer Science) with 1+ years of academic/industry experience; or a Master's Degree in a relevant quantitative field with 3+ years of industry experience
• Strong experience in data science and statistical analysis using clinical trial or electronic health records data, particularly in a pharma R&D context
• Experience developing and validating statistical and machine learning models on high-dimensional data for time-to-event, longitudinal, and multivariate outcomes
• Experience in the application of AI/ML and proficiency in Python, R, SQL, and cloud platforms (e.g., AWS, Azure, Databricks)
• Familiarity with clinical trial design, drug development processes, and the role of biomarkers in regulatory and clinical decision-making
• A perspective on leveraging innovative approaches to expedite drug development and address the complexities of emerging data types
• Strong problem-solving, collaboration, and communication skills, with the ability to handle several concurrent, fast-paced projects independently and as part of a team

Preferred Qualifications:

• Experience with genomics, proteomics, imaging, flow cytometry, or immunobiology datasets from clinical trials
• Experience with NLP, causal ML, explainable AI, and survival analysis/time-to-event modelling
• Knowledge of molecular biology and understanding of disease pathways
• Experience with real-world data (RWD/RWE) sources and associated analytical methods
• Familiarity with digital health data and wearable/sensor-derived data types
• Experience with cloud-based scalable compute and deployment patterns for large-scale data processing and model training

#LI-Hybrid

We hire for skills and capabilities, not just credentials – if this role excites you, but doesn’t perfectly match your resume, we encourage you to apply anyway.

How We Work

Where you work matters – because collaboration, innovation and patient impact happen in many settings. Our roles are structured across four work models: site-essential, site-by-design, field-based and remote-by-design. The model assigned to this role is based on its core responsibilities. Learn more at https://careers.bms.com/ways-of-working.

Supporting People with Disabilities

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [email protected]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Bristol Myers Squibb is Disability Confident – Employer

A UK Government scheme

Candidate Rights

BMS will consider qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

For roles based in Los Angeles County only:  If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

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